Jim McAfee's Blog Spot

Sunday, May 09, 2021

Pathogenic Priming

 A Little Humor


One of the most delightful weekends I had spent since moving to California six months before was nearing an end as two teenage girls approached me while I was counting out my vitamins. "What are all those pills for?" one of them asked. "Well," I explained, "these two are for beautiful eyes, this one for long willowy legs, that little one is for pearly, white teeth..." and as I was waxing on, the other girl interrupted me with, "Haven't been taking them long, have you?" Luci Swindoll, Joy Breaks, p. 112.

Pathogenic Priming
"In SARS, a type of “priming” of the immune system was observed during animal studies of SARS spike protein-based vaccines leading to increased morbidity and mortality in vaccinated animals who were subsequently exposed to wild SARS virus." The above is a summary of a potential problem with the vaccines developed to fight Covid-19. Animal studies such as those discussed in this study, related to the SARS vaccine, were not done before the development of the Covid-19 vaccines due to the rush to market (operation warp speed).
This study notes that 1/3 of the proteins in the Covid-19 vaccines have the potential to create problems with immune function contributing to autoimmune disease upon subsequent exposure to similar viruses. This is referred to as "pathogenic priming" by the author of the article. Pathogenic priming can also result from infection by viruses.
The phenomena of pathogenic priming helps to explain why damaging effects from infection with Covid-19 or vaccination for the disease can result in serious problems such as lung damage long after the initial infection or vaccination.
The author of this article notes that studies of pathogenic priming have not been done on Covid-19 vaccines, but that this is a definite risk. He concludes with the following: "Such studies should be undertaken before use of any vaccine against SARS-CoV-2 is used in humans." This is obviously not going to happen which means that we may see many negative longer-term effects of these vaccinations before the issue of pathogenic priming is clarified. In the meantime, the vaccine manufacturers run to the bank with profits from vaccination with no liability for damages and no proof that the vaccines can cause this type of damage until studies are conducted which may be well after most of the world has already been vaccinated.
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Vitamin B3 and Lung Damage
"Lung damage is a major hurdle to recovery in those severe patients. Through producing various growth factors, MSCs may help repair of the damaged lung tissue. It is important to mention that various studies have shown that in animal models with bleomycin-induced lung injury, vitamin B3 (niacin or nicotinamide) is highly effective in preventing lung tissue damage [7]. It might be a wise approach to supply this food supplement to the COVID-19 patients."
In China mesenchymal stromal/stem cells (MSCs) are being tested to see if they can promote healing of damaged lung tissue from Covid-19. This strategy is still unproven, but the author does observe in the above quote that a natural nutrient, vitamin B3, is highly effective in preventing lung damage and should probably be administered to COVID-19 patients.
Vitamin B3 is available as a flush form (niacin) which can be unpleasant to some people, and as niacinamide which is a non-flush form. The latter is usually used in supplements. In the hamster study on vitamin B3 the niacin form was more effective in preventing lung damage.


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